An introduction to bioreactor hydrodynamics and gasliquid. Pdf gasliquid mass transfer in bioreactor with three. Biochemicals from food waste and recalcitrant biomass via. Liquid velocities as a function of superficial gas velocity in the riser. Oxygen mass transfer in sparged stirred tank bioreactors has been studied.
Pdf gasliquid mass transfer in bioreactor with threephase. Pdf mass transfer in bioreactors eleazar escamilla. A rate limiting step in these processes is the low mass transfer between the gas and the liquid phases. For example, when dye is dropped into a cup of water, mass transfer processes are responsible for the movement of dye molecules through the water until equilibrium is established and the concentration is uniform. Such bioreactors have shown promising results in increasing the volumetric mass transfer coefficient kla. Gasliquid mass transfer in bioreactor with threephase inverse fluidized bed article pdf available in bioprocess and biosystems engineering 235. Effects of hydrocarbon additions on gasliquid mass transfer coefficients in biphasic bioreactors. Mass transfer in a singleuse angledshaft aerated stirred. In the present study the oxygen mass transfer from the gas to the aqueous phase in a threephase inverse fluidized bed tpifb has been studied. Investigation and modeling of gasliquid mass transfer in a. The complexity grows further once the relationships between each gas component and, for example, the bacteria in a bioreactor are considered.
Gasliquid mass transfer is commonly the ratelimiting step in industrialscale biochemical reactions. Gasliquid mass transfer in dual impeller bioreactor sciencedirect. An introduction to bioreactor hydrodynamics and gasliquid mass transfer. The rate of oxygen mass transfer into a culture in a bioreactor is. Prediction of gasliquid mass transfer coefficient in sparged stirred tank bioreactors. Pdf prediction of gasliquid mass transfer coefficient. Pdf effects of hydrocarbon additions on gasliquid mass. Pdf in the present study the oxygen mass transfer from the gas to the aqueous phase in a threephase inverse fluidized bed tpifb has been studied. The gasliquid mass transfer coefficient k l a in a fermenter is known to be a strong function of mode of energy dissipation and physicochemical properties of the.
Therefore, the gasliquid mass transfer area results from the surface of the rotating bulk liquid and of the liquid film on the reactor wall as schematically shown in fig. Therefore, novel techniques that can enhance the gasliquid mass transfer including membrane and tricklebed bioreactors were discussed. For this reason, bioreactor design and scaleup focuses on. Gasliquid mass transfer in bioreactor with threephase inverse. Characterization of the gasliquid mass transfer in. In this paper, the effects of the impeller speed, the volumetric gas flow rate, and the impeller type on the volumetric gasliquid mass transfer coefficient in a singleuse unbaffled angledshaft bioreactor applicable for the animal cell culture were analyzed and compared with those attained for the baffled verticalshaft bioreactors. The gasliquid mass transfer coefficient in a fermenter is known to be a strong function of mode of energy dissipation and physicochemical properties of the liquid media. Understanding of the mass transfer behaviour in bioreactors would result in improved reactor designs, reactor operation, and modelling tools.
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